His research interests are in adaptive video processing and delivery for real time applications, including 360o video coding, computer vision for healthcare applications using deep learning methods, interactive and distributed analytics of large-scale image and video databases, and mHealth and eHealth systems and services. He has published more than 80 peer-reviewed journal and conference papers, and book chapters, in these areas, including 1 patent. He was the lead Guest Editor of IET Healthcare Technology Letters, Special Issue on mHealth-Emerging Mobile Health Systems and Services (10 papers), published in 2016 and the Guest Editor of the research topic on Connected Health: Status and Trends (11 papers) published by Frontiers in Digital Health in 2020. Since 2021, Dr. Panayides has been an Associate Editor of the IEEE Journal of Biomedical and Health Informatics (J-BHI) (Impact Factor: 7.021).

Dr. Panayides is actively involved in national and international research projects, funded by the European Commission, the Research and Innovation Foundation of Cyprus, and the National Science Foundation, USA. He is also serving as an expert reviewer for H2020 proposals. Dr. Panayides has managed funding as principal investigator (PI) or co-PI of more than €1.7 million with €0.5 million awarded for personal fellowships. In 2016, he co founded 3AHealth (3ahealth.com), a start-up company based in Cyprus that provides innovative and citizen-centric solutions throughout the healthcare pathway. Dr. Panayides was the deputy national architect of Cyprus’ EU Digital Covid Certificate (https://www.eudcc.gov.cy/) portal.