Our Work
CYENS Centre of Excellence is a leading Research and Innovation hub specializing in Interactive Media, Smart Systems, and Emerging Technologies. As the only organization in Cyprus dedicated to immersive technologies, it plays a vital role in advancing knowledge and facilitating technology transfer across the region. This Centre is the result of a unique collaboration between three public universities—the University of Cyprus, the Cyprus University of Technology.
SEM-CMR
Deep semantic volumetric reconstruction of cardiac magnetic resonance imaging
Starting date
18 May 2026
End date
17 May 2027

SEM-CMR
Deep semantic volumetric reconstruction of cardiac magnetic resonance imaging
SEM-CMR aims to advance cardiac magnetic resonance (CMR) imaging by developing artificial intelligence methods capable of reconstructing 3D images of myocardial perfusion from routine clinical scans. Coronary artery disease remains the leading cause of death worldwide, yet current CMR perfusion imaging captures only a limited portion of the heart, potentially overlooking clinically important regions of reduced blood flow. SEM-CMR addresses this challenge by combining patient-specific anatomical information with semantic deep learning to generate physiologically meaningful whole-heart perfusion reconstructions, validated against invasive reference techniques. Beyond improving the detection of myocardial ischaemia, the reconstructed 3D heart provides a tailored anatomical reference frame for each patient, enabling the co-registration and joint analysis of complementary CMR biomarkers, such as perfusion, function and tissue characterization, paving the way towards more comprehensive and personalised cardiac assessment. Using retrospective clinical datasets, the project will establish the feasibility of this approach while laying the scientific and methodological foundations for a future European Research Council (ERC) Consolidator Grant in AI-driven, physiology-aware cardiac imaging. The project is funded by the Republic of Cyprus, through the Research and Innovation Foundation.
Contact Person:
Dr Xenios Milidonis
Email: x.milidonis@cyens.org.cy